Plant-derived sulfur containing natural products produced as a response to biotic and abiotic stresses: A review of their structural diversity and medicinal importance
Plant-derived sulfur-containing secondary metabolites constitute a small group of low-molecular weight natural products, which play a vital role in plant-pest interactions in numerous plant families andrepresent major defense molecules in the Asteraceae, Alliaceae, and Brassicaceae families.
In this review we highlight the crucial role of environmental stress factors in the production of S-containing secondary metabolites. Furthermore, we describe a serendipitous variety of plant-derived sulfur-containing natural products produced or induced under biotic and abiotic stress and their structural diversity, promising pharmacological properties for use by humans, and beneficial effects for plants. Specifically, cruciferous phytoalexins are known as elicit plant defense molecules. Glucosinolates are candidates for tumorpreventive effects. Cysteine sulfoxides found in garlic are considered as profound antimicrobial agents. In this review, we discuss types of S bonds in the molecules and their relevance for the medicinal effect as well as the biological activities of sulfur-containing secondary metabolites and possible future avenues.
This work is licensed under a Creative Commons Attribution 4.0 International License.
From Volume 92 (2019) on, the content of the journal is licensed under the Creative Commons Attribution 4.0 License. Any user is free to share and adapt (remix, transform, build upon) the content as long as the original publication is attributed (authors, title, year, journal, issue, pages) and any changes are labelled.
The copyright of the published work remains with the authors. If you want to use published content beyond what the CC-BY license permits, please contact the corresponding author, whose contact information can be found on the last page of the respective article. In case you want to reproduce content from older issues (before CC BY applied), please contact the corresponding author to ask for permission.